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06/15/2026

Provider Alert: Emerging Substances in Illicit Drug Supply

North Carolina clinicians should be aware of the increasing detection of medetomidine, a potent veterinary sedative, and cychlorphine, a highly potent synthetic opioid, in the illicit opioid supply. Both substances have recently been identified in fentanyl and polysubstance drug samples across the United States, including reports in North Carolina. More information can be found in this NCDHHS clinician memo.

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